HOLISTIC WEIGHT LOSS

Pharmacologic Treatment of Obesity


Obesity


Obesity is a condition which can lead to major morbidity and mortality as well as chronic medical conditions such as diabetes mellitus, hypertension, hyperlipidemia, cardiovascular disease, sleep apnea and others.

After ruling out hormonal or other abnormalities which can lead to weight gain the mainstay of treatment is of course lifestyle modification including a healthy diet and regular physical activity. However in many cases lifestyle modification is not enough to achieve the desired weight loss and pharmacologic treatment is indicated on top of diet and exercise. Other options are bariatric surgery.


Weight Loss Injections

Currently the most commonly used agents for treatment of obesity belong to a class of medications called GLP-1 agonists. Formulations include daily tablets (semaglutide) or weekly injections (semaglutide, tirzepatide) with injections more effective than tablets in achieving weight loss.


  • Origins & approval:
  • Side Effects:
  • Contraindications:
Origins & approval:
  • Initially approved for managing type 2 diabetes mellitus.
  • Subsequently gained approval for weight loss.
Side Effects:

Common side effects include:

  • Nausea
  • Vomiting
  • Fatigue
  • Pancreatitis (inflammation of the pancreas) and gallstones have also been reported albeit less frequently.
Contraindications:

Contraindications may include:

  • Allergic reactions to GLP-1 agonists.
  • Personal or family history of a specific type of thyroid cancer (medullary cancer of the thyroid).

Bariatric surgery services at Harley Street:

LEARN MORE ABOUT OUR WEIGHT LOSS CLINIC


Dr. Pierre Salim Najm - Consultant Endocrinologist
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DR. PIERRE SALIM NAJM

Dr Chawki Mounayer
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DR. CHAWKI MOUNAYER

Dr. Manal Adly Aziz
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DR. MANAL ADLY AZIZ

Dr. Hady Jerdak
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DR. HADY JERDAK

Abir Hobballah Dietitian
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ABIR HOBBALLAH



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If your BMI is 18.5 to <25, it falls within the normal.
If your BMI is 25.0 to <30, it falls within the overweight range.
If your BMI is 30.0 or higher, it falls within the obese range.

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